Postmenopausal women whose breast cancer is fueled by hormones are typically prescribed aromatize inhibitors (ALs) for five years after the surgery or primary treatment. The side effects can sometimes cause harmful side effects such as bone loss and heart problems. The most common side effect experienced by 50% of women is arthralgia, persistent joint pain and is reported the main reason women stop taking the drug.
The HOPE study (Hormone and Physical Exercise) examined 121 women who were physically inactive but able to exercise and who had been taking ALs 6 months. Participants that reported at least mild joint pain were randomized receiving standard care or to participate in a twice weekly supervised resistance training sessions and at least 150 minutes of moderate intensity aerobic exercise.
The research study reports that after 12 months of consistent exercise the women in the exercise group experienced 20 to 30% decrease in joint pain, in addition to other benefits, such as weight loss, cardio respiratory fitness. Participants receiving standard care reported an increase in joint pain. CURE Spring 2014
Jacqueline’s comments: The article did not mention of any improvements of functional fitness which is expected from a resistance training program. Since this was not the objective of the study no pre- or post testing may have been performed to assess. My experience in instructing supervised and targeted exercise programs that emphasize resistance training that dramatic improvement in functional fitness are expected, especially in previously inactive individuals.
When you are interested in taking a supervised and personalized exercise training group program I am teaching Revive; Exercise Recovery Program, Workout for: Weight-Loss, better health and the Ageless Athlete, as well as the Diabetes Intervention Prevention Exercise Program (DIP)through the THPRD Elsie Stuhr in Beaverton. Private in-home training to better manage medical conditions is another possibility.