Exercise has shown tremendous promise as a neuroprotective intervention (Fleshner et al. 2011; Head, Singh & Bugg, 2012; McEwen 2012). Research has identified several ways that exercise protects the brain from stress—and even reverses the effects of chronic stress on the brain (Stranahan & Mattson 2012; Rothman & Mattson 2012). Exercise increases brain-derived neurotrophic factor, which maintains brain health, supports brain growth and combats the negative effects of stress. Exercise seems to enhance BDNF specifically in the prefrontal cortex and hippocampus, the two regions most susceptible to stress-related damage. Exercise also triggers the brain’s self-repair processes, which may help reverse any stress-related neurotoxicity. Finally, exercise activates the brain’s stress-calming system, releasing a neurotransmitter called GABA, which helps restore balance in the autonomic nervous system. When we exercise regularly, we naturally engage all of these neuroprotective processes. Over time, exercise can create a “stress-resistant” brain that is less sensitive to threat and recovers more quickly from stress (Fleshner et al. 2011).