What does pain mean during a workout? Sometimes pain is a sign to pull back. Sometimes pain means you need to make adjustments in your posture, amount of weight you're lifting, form, technique, alignment, or timing. Sometimes a little pain leads to great improvements... And I love the saying that sometimes pain is just weakness leaving your body! So know your body, know your pain threshold and know when the "No Pain, No Gain" saying is acceptable and when it is not.